Sdr16c6^em1Nyk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sdr16c6^em1Nyk
• Name: short chain dehydrogenase/reductase family 16C, member 6; endonuclease-mediated mutation 1, Natalia Y Kedishvili
• MGI ID: MGI:6400367
• Gene: Sdr16c6 Location: Chr4:4055926-4077514 bp, - strand Genetic Position: Chr4, 2.27 cM
• Alliance: Sdr16c6^em1Nyk page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 1837 bp from exon 5. (J:283063)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sdr16c6 Mutation: 16 strains or lines available

Notes

This allele was generated in conjunction with Sdr16c5^em1Nyk and are together referred to as DKO2.

References

• Original: J:283063 Wu L, et al., Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands. J Biol Chem. 2019 Nov 8;294(45):17060-17074
• All: 1 reference(s)