Hdnr^em1Bbr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hdnr^em1Bbr
• Name: Hand2 downstream lncRNA; endonuclease-mediated mutation 1, Benoit G Bruneau
• MGI ID: MGI:6400426
• Synonyms: Handlr^-
• Gene: Hdnr Location: Chr8:57785470-57807615 bp, + strand Genetic Position: Chr8, 29.8 cM
• Alliance: Hdnr^em1Bbr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR guide RNAs were designed to induce a 2 to 3 kb deletion flanking the transcript start site and/or promoter. (J:284183)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hdnr Mutation: 0 strains or lines available

References

• Original: J:284183 George MR, et al., Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. Development. 2019 Dec 9;146(23):dev185314
• All: 1 reference(s)