Atcayos^em1Bbr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Atcayos^em1Bbr
• Name: ataxia, cerebellar, Cayman type, opposite strand; endonuclease-mediated mutation 1, Benoit G Bruneau
• MGI ID: MGI:6400428
• Gene: Atcayos Location: Chr10:81030525-81044204 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Atcayos^em1Bbr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR guide RNAs were designed to induce a 2 to 3 kb deletion flanking the transcript start site and/or promoter. (J:284183)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atcayos Mutation: 1 strain or line available

References

• Original: J:284183 George MR, et al., Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. Development. 2019 Dec 9;146(23):dev185314
• All: 1 reference(s)