Rubie^em1Bbr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rubie^em1Bbr
• Name: RNA upstream of Bmp4 expressed in inner ear; endonuclease-mediated mutation 1, Benoit G Bruneau
• MGI ID: MGI:6400429
• Gene: Rubie Location: Chr14:46805788-46813308 bp, - strand Genetic Position: Chr14, 24.11 cM
• Alliance: Rubie^em1Bbr page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR guide RNAs were designed to induce a 2 to 3 kb deletion flanking the transcript start site and/or promoter. (J:284183)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rubie Mutation: 0 strains or lines available

References

• Original: J:284183 George MR, et al., Minimal in vivo requirements for developmentally regulated cardiac long intergenic non-coding RNAs. Development. 2019 Dec 9;146(23):dev185314
• All: 1 reference(s)