Relt^tm1Hlee
Targeted Allele Detail

Summary

• Symbol: Relt^tm1Hlee
• Name: RELT tumor necrosis factor receptor; targeted mutation 1, Ho Lee
• MGI ID: MGI:6400520
• Synonyms: RELT^-
• Gene: Relt Location: Chr7:100495054-100512653 bp, - strand Genetic Position: Chr7, 54.44 cM
• Alliance: Relt^tm1Hlee page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266480
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3-6 were replaced with a puromycin resistance gene cassette through homologous recombination. (J:266480)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Relt Mutation: 24 strains or lines available

References

• Original: J:266480 Choi BK, et al., RELT negatively regulates the early phase of the T-cell response in mice. Eur J Immunol. 2018 Oct;48(10):1739-1749
• All: 1 reference(s)