Htt^tm5Detl
Targeted Allele Detail

Summary

• Symbol: Htt^tm5Detl
• Name: huntingtin; targeted mutation 5, Peter J Detloff
• MGI ID: MGI:6400708
• Synonyms: HdhQ350
• Gene: Htt Location: Chr5:34919084-35069878 bp, + strand Genetic Position: Chr5, 17.92 cM
• Alliance: Htt^tm5Detl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250587
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• This allele carries 350 CAG repeat units in the first exon of the endogeneous gene. (J:250587)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Htt Mutation: 178 strains or lines available

References

• Original: J:250587 Cao JK, et al., Sex-dependent behavioral impairments in the HdhQ350/+ mouse line. Behav Brain Res. 2018 Jan 30;337:34-45
• All: 1 reference(s)