Prlr^tm1.1Skkm
Targeted Allele Detail

Summary

• Symbol: Prlr^tm1.1Skkm
• Name: prolactin receptor; targeted mutation 1.1, Seung K Kim
• MGI ID: MGI:6400798
• Synonyms: Prlr^f
• Gene: Prlr Location: Chr15:10177324-10349266 bp, + strand Genetic Position: Chr15, 5.23 cM
• Alliance: Prlr^tm1.1Skkm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:268568
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 5 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin cassette inserted downstream of exon 5. (J:268568)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prlr Mutation: 44 strains or lines available

References

• Original: J:268568 Kim H, et al., Ectopic serotonin production in beta-cell specific transgenic mice. Biochem Biophys Res Commun. 2018 Jan 8;495(2):1986-1991
• All: 2 reference(s)