Ddx41^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Ddx41^tm1.1Arte
• Name: DEAD box helicase 41; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6401407
• Synonyms: DDX41-flp
• Gene: Ddx41 Location: Chr13:55678223-55684471 bp, - strand Genetic Position: Chr13, 30.06 cM
• Alliance: Ddx41^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265023
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted into introns 6 and 9. An FRT site flanked antibiotic resistance gene cassette that was also inserted, was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 7-9 floxed. (J:265023)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddx41 Mutation: 46 strains or lines available

References

• Original: J:265023 Stavrou S, et al., DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection. mBio. 2018 Jun 5;9(3)
• All: 2 reference(s)