Ss18l1^em1Zqi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ss18l1^em1Zqi
• Name: SS18, nBAF chromatin remodeling complex subunit like 1; endonuclease-mediated mutation 1, Zilong Qiu
• MGI ID: MGI:6401515
• Synonyms: Crest^-
• Gene: Ss18l1 Location: Chr2:179684302-179711994 bp, + strand Genetic Position: Chr2, 102.56 cM
• Alliance: Ss18l1^em1Zqi page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology using sgRNA 5'-ATGCAGGGCCAGATCGGTAA-3' generated a knock-out allele. (J:278840)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ss18l1 Mutation: 18 strains or lines available

References

• Original: J:278840 Cheng C, et al., Loss of CREST leads to neuroinflammatory responses and ALS-like motor defects in mice. Transl Neurodegener. 2019;8:13
• All: 1 reference(s)