Phpt1^tm1.1Eys
Targeted Allele Detail

Summary

• Symbol: Phpt1^tm1.1Eys
• Name: phosphohistidine phosphatase 1; targeted mutation 1.1, Edward Y Skolnik
• MGI ID: MGI:6401823
• Synonyms: PHPT-1^-
• Gene: Phpt1 Location: Chr2:25463442-25465236 bp, - strand Genetic Position: Chr2, 17.44 cM, cytoband A3
• Alliance: Phpt1^tm1.1Eys page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262099
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J/J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Phpt1 Mutation: 12 strains or lines available

References

• Original: J:262099 Srivastava S, et al., Regulation of KATP Channel Trafficking in Pancreatic beta-Cells by Protein Histidine Phosphorylation. Diabetes. 2018 May;67(5):849-860
• All: 1 reference(s)