Tle6^tm1Lil
Targeted Allele Detail

Summary

• Symbol: Tle6^tm1Lil
• Name: transducin-like enhancer of split 6; targeted mutation 1, Lei Li
• MGI ID: MGI:6402939
• Synonyms: Tle6^Null
• Gene: Tle6 Location: Chr10:81426738-81436907 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Tle6^tm1Lil page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276268
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A neomycin resistance cassette replaced exons 1 and 2. (J:276268)

Expression

In Mice Carrying this Mutation:	2 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tle6 Mutation: 61 strains or lines available

References

• Original: J:276268 Yu XJ, et al., The subcortical maternal complex controls symmetric division of mouse zygotes by regulating F-actin dynamics. Nat Commun. 2014 Sep 11;5:4887
• All: 2 reference(s)