Uqcrc1^tm1Zzuo
Targeted Allele Detail

Summary

• Symbol: Uqcrc1^tm1Zzuo
• Name: ubiquinol-cytochrome c reductase core protein 1; targeted mutation 1, Zhiyi Zuo
• MGI ID: MGI:6403206
• Synonyms: UQCRC1^-
• Gene: Uqcrc1 Location: Chr9:108765701-108778691 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Uqcrc1^tm1Zzuo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:285933
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Genomic sequence, representing a 3' part of exon 3, the entire intron 3 and a 5' part of exon 4, was replace with a lacZ-neo cassette. (J:285933)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uqcrc1 Mutation: 29 strains or lines available

References

• Original: J:285933 Shan W, et al., Critical role of UQCRC1 in embryo survival, brain ischemic tolerance and normal cognition in mice. Cell Mol Life Sci. 2019 Apr;76(7):1381-1396
• All: 2 reference(s)