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Cyp2ctm1104Arte
Targeted Allele Detail
Summary
Symbol: Cyp2ctm1104Arte
Name: cytochrome P450, family 2, subfamily c cluster; targeted mutation 1104, TaconicArtemis
MGI ID: MGI:6404559
Synonyms: Cyp2cKO, Del(19Cyp2c55-Cyp2c70)Arte
Gene: Cyp2c  Location: unknown  Genetic Position: Chr19, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:241121
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
  Cyp2ctm1104Arte involves 19 genes/genome features (Gm23800, Cyp2c55, Gm3875 ...) View all
 
Mutation detailsCre-mediated recombination between a thymidine kinase expression cassette, hygromycin resistance cassette, loxP site, lox5171 and FRT site inserted into intron 6 of Cyp2c55 and an f3 site, promoter, loxP site, neomycin resistance gene, thymidine kinase expression cassette inserted into intron 1 of Cyp2c70 deleted the intervening sequence. (J:241121)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyp2c Mutation:  0 strains or lines available
References
Original:  J:241121 Scheer N, et al., Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines. Mol Pharmacol. 2012 Dec;82(6):1022-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory