Usp13^em1Nmw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Usp13^em1Nmw
• Name: ubiquitin specific peptidase 13 (isopeptidase T-3); endonuclease-mediated mutation 1, Nathaniel M Weathington
• MGI ID: MGI:6406217
• Gene: Usp13 Location: Chr3:32871695-32992220 bp, + strand Genetic Position: Chr3, 15.88 cM
• Alliance: Usp13^em1Nmw page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted exon 6 and intron 18 (chromosome 3 between position 32,865,806 and 32,917,828). (J:285981)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Usp13 Mutation: 46 strains or lines available

References

• Original: J:285981 Li L, et al., The deubiquitinase USP13 stabilizes the anti-inflammatory receptor IL-1R8/Sigirr to suppress lung inflammation. EBioMedicine. 2019 Jul;45:553-562
• All: 2 reference(s)