Slnem1Cyh
Endonuclease-mediated Allele Detail
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| Symbol: |
Slnem1Cyh |
| Name: |
sarcolipin; endonuclease-mediated mutation 1, Ya-Hui Chi |
| MGI ID: |
MGI:6407424 |
| Gene: |
Sln Location: Chr9:53757535-53761133 bp, + strand Genetic Position: Chr9, 29.24 cM, cytoband C
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| Alliance: |
Slnem1Cyh page
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Endonuclease-mediated (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: CRISPR/Cas9 technology generated a 31 amino acid deletion in exon 2. Western blot analysis confirmed absence of protein expression.
(J:284048)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Sln Mutation: |
11 strains or lines available
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| Original: |
J:284048 Wang WP, et al., Progerin in muscle leads to thermogenic and metabolic defects via impaired calcium homeostasis. Aging Cell. 2020 Feb;19(2):e13090 |
| All: |
1 reference(s) |
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Analysis Tools
