Tenm1^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tenm1^em1(IMPC)Tcp
• Name: teneurin transmembrane protein 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6414509
• Gene: Tenm1 Location: ChrX:41616743-42518003 bp, - strand Genetic Position: ChrX, 23.21 cM, cytoband A2
• Alliance: Tenm1^em1(IMPC)Tcp page
• IMPC: Tenm1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project TCPR1561 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GCACAGCATGACAGACTTAC targeting the 5' side and TGAATAATAGCTTAAGTACC targeting the 3' side of a critical region. This resulted in a 317-bp deletion, ChrX:42937711-42938027 (GRCm38). (J:265051)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tenm1 Mutation: 23 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)