Eny2em1(IMPC)Bay
Endonuclease-mediated Allele Detail
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Symbol: |
Eny2em1(IMPC)Bay |
Name: |
ENY2 transcription and export complex 2 subunit; endonuclease-mediated mutation 1, Baylor College of Medicine |
MGI ID: |
MGI:6414562 |
Synonyms: |
Eny2- |
Gene: |
Eny2 Location: Chr15:44291488-44301652 bp, + strand Genetic Position: Chr15, 16.91 cM
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Alliance: |
Eny2em1(IMPC)Bay page
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IMPC: |
Eny2 gene page |
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Eny2em1(IMPC)Bay/Eny2em1(IMPC)Bay mice exhibit embryonic lethality, with embryos recovered at E3.5 as early blastocysts but not at E7.5. Blastocysts hatch from the zona pellucida and form irregular outgrowths with no obvious inner cell mass colony or trophoblast giant cells.
Show the 1 phenotype image(s) involving this allele.
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele from IMPC was generated at Bayor College of Medicine by injecting CAS9 Protein and 4 guide sequences GAACTGTGTTTAATTACCTCAGG, ACAGCTGGAGAATATTACCCAGG, TTAGGTACATAAGTGCTTAATGG, TTGTGTCATTAGAGCAAATTTGG, which resulted in a Exon Deletion.
(J:265051)
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Inheritance: |
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Not Specified |
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023; |
All: |
4 reference(s) |
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