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Slc1a3tm1.1(cre/ERT2)Wsj
Targeted Allele Detail
Summary
Symbol: Slc1a3tm1.1(cre/ERT2)Wsj
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3; targeted mutation 1.1, Walker Jackson
MGI ID: MGI:6414570
Synonyms: Slc1a3-CreERT2
Gene: Slc1a3  Location: Chr15:8663608-8740248 bp, - strand  Genetic Position: Chr15, 3.82 cM, cytoband A2
Alliance: Slc1a3tm1.1(cre/ERT2)Wsj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Slc1a3tm1.1(cre/ERT2)Wsj expression driven by 1 gene
 
Mutation detailsThe sequence encoding the cre/ERT2 fusion protein was inserted in place of the stop codon. A 2A peptide separates the two proteins during translation. Flp-mediated recombination removed the neomycin selection cassette. (J:82809, J:304813)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc1a3 (mouse)
Summary of all recombinase alleles driven by Slc1a3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slc1a3 Mutation:  70 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory