Jakmip3^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jakmip3^em1(IMPC)J
• Name: janus kinase and microtubule interacting protein 3; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:6414769
• Gene: Jakmip3 Location: Chr7:138542459-138663892 bp, + strand Genetic Position: Chr7, 83.0 cM, cytoband A1.3
• Alliance: Jakmip3^em1(IMPC)J page
• IMPC: Jakmip3 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTCCGAGGATACTGCACAG and TTCCCCAGAGATACCCACCA, which resulted in a 711 bp deletion beginning at Chromosome 7 position 138,989,077 bp and ending after 138,989,787 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000452940 (exon 2) and 468 bp of flanking intronic sequence including the splice acceptor, donor and start site and is predicted to generate a null allele. (J:188991)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Jakmip3 Mutation: 30 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)