Tg(Adipoq-Zc3h10*)#Hsul
Transgene Detail

Summary

• Symbol: Tg(Adipoq-Zc3h10*)#Hsul
• Name: transgene insertion, Hei Sook Sul
• MGI ID: MGI:6415579
• Synonyms: AQ-Zc3h10-mutZF1/2
• Transgene: Tg(Adipoq-Zc3h10*)#Hsul Location: unknown
• Alliance: Tg(Adipoq-Zc3h10*)#Hsul page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Adipoq-Zc3h10*)#Hsul expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Zc3h10	protein lacks the RNA binding ability

• Mutation details: Expression of a mutant Zc3h10 lacking the RNA binding ability is driven by a -5.2kb adiponectin promoter. Expression levels are increased 2- and 1.5-fold in brown and inguinal white adipose tissue, respectively. No line numbers were provided. (J:287066)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:287066 Yi D, et al., Zc3h10 Acts as a Transcription Factor and Is Phosphorylated to Activate the Thermogenic Program. Cell Rep. 2019 Nov 26;29(9):2621-2633.e4
• All: 1 reference(s)