Firre^em1.1Rinn
Endonuclease-mediated Allele Detail

Summary

• Symbol: Firre^em1.1Rinn
• Name: functional intergenic repeating RNA element; endonuclease-mediated mutation 1.1, John Rinn
• MGI ID: MGI:6416507
• Gene: Firre Location: ChrX:49651997-49724198 bp, - strand Genetic Position: ChrX, 26.53 cM
• Alliance: Firre^em1.1Rinn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282020
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting inserted loxP site and cre-recombination removed 40 kb (mm10; chrX:50,555,286-50,637,116). (J:282020)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Firre Mutation: 14 strains or lines available

References

• Original: J:282020 Andergassen D, et al., In vivo Firre and Dxz4 deletion elucidates roles for autosomal gene regulation. Elife. 2019 Nov 18;8:e47214
• All: 1 reference(s)