Grp^tm2Zfc
Targeted Allele Detail

Summary

• Symbol: Grp^tm2Zfc
• Name: gastrin releasing peptide; targeted mutation 2, Zhou-Feng Chen
• MGI ID: MGI:6430561
• Synonyms: Grp^F, Grp^tm1Zfc
• Gene: Grp Location: Chr18:66005891-66019667 bp, + strand Genetic Position: Chr18, 38.98 cM
• Alliance: Grp^tm2Zfc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 1, and an FRT-flanked neomycin selection cassette followed by a second loxP site downstream of exon 1 of the gene. (J:288162)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grp Mutation: 30 strains or lines available

Notes

The version of this allele that does not contains the neomycin selection cassette, Grp^tm1.1Zfc, has been analyzed.

References

• Original: J:288162 Barry DM, et al., Exploration of Sensory and Spinal Neurons Expressing GRP in Itch and Pain. bioRxiv. 2018
• All: 3 reference(s)