Il17a^{em4(icre)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il17a^{em4(icre)Smoc}
• Name: interleukin 17A; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
• MGI ID: MGI:6430676
• Synonyms: Il17a^{em1(Linker-iCre-polyA(SV40))Smoc}
• Gene: Il17a Location: Chr1:20801129-20804720 bp, + strand Genetic Position: Chr1, 6.45 cM, cytoband A
• Alliance: Il17a^{em4(icre)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Il17a^{em4(icre)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Il17a (MGI:107364)

• Mutation details: CRISPR/Cas9 genome editing technology was used to insert a Linker-iCre-polyA expression cassette into the gene stop codon. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Il17a (mouse) Summary of all recombinase alleles driven by Il17a. Alliance mouse Il17a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17a Mutation: 25 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)