Epcam^{em1(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Epcam^{em1(cre/ERT2)Smoc}
• Name: epithelial cell adhesion molecule; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6430709
• Synonyms: Epcam-2A-CreERT2, Epcam^{em1(2A-CreERT2)Smoc}
• Gene: Epcam Location: Chr17:87943407-87958555 bp, + strand Genetic Position: Chr17, 57.87 cM
• Alliance: Epcam^{em1(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Epcam^{em1(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Epcam (MGI:106653)

• Mutation details: A 2A-CreERT2 co-expression cassette is inserted before the 3'UTR region of the Epcam gene via CRISPR/Cas mediated recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Epcam (mouse) Summary of all recombinase alleles driven by Epcam. Alliance mouse Epcam gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Epcam Mutation: 33 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)