1700121C10Rik^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: 1700121C10Rik^em1Smoc
• Name: RIKEN cDNA 1700121C10 gene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6430726
• Synonyms: 1700121C10Rik^-
• Gene: 1700121C10Rik Location: Chr8:95520793-95529100 bp, - strand Genetic Position: Chr8, Syntenic
• Alliance: 1700121C10Rik^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This locus consists of three exons and its expression leads to two transcripts that are testis-specific long noncoding RNAs (lncRNAs). CRISPR/Cas9 genome editing technology was used to delete the entire transcribed region. RT-PCR and qRT-PCR analyses confirmed the absence of expression at the RNA level in the testes of homozygous mutant males. (J:238766, J:288171)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any 1700121C10Rik Mutation: 1 strain or line available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 2 reference(s)