Rr76^em1Ona
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr76^em1Ona
• Name: regulatory region 76; endonuclease-mediated mutation 1, Osamu Nakagawa
• MGI ID: MGI:6438145
• Synonyms: -211k^delta
• Gene: Rr76 Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: Rr76^em1Ona page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting removed a 3297 bp region (C57BL/6 reference genome GRCm39) containing the 2535 bp ventricular enhancer -221 kb from Hey2. (J:288309)

Expression

In Mice Carrying this Mutation:

10 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr76 Mutation: 0 strains or lines available

References

• Original: J:288309 Ihara D, et al., Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors. Dev Biol. 2020 May 15;461(2):124-131
• All: 1 reference(s)