Tbx20^em1Ona
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tbx20^em1Ona
• Name: T-box 20; endonuclease-mediated mutation 1, Osamu Nakagawa
• MGI ID: MGI:6438147
• Synonyms: Tbx20^ko
• Gene: Tbx20 Location: Chr9:24632108-24685580 bp, - strand Genetic Position: Chr9, 10.25 cM
• Alliance: Tbx20^em1Ona page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed exon 2 containing part of the T-box domain. (J:288309)

Expression

In Mice Carrying this Mutation:	9 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbx20 Mutation: 36 strains or lines available

References

• Original: J:288309 Ihara D, et al., Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors. Dev Biol. 2020 May 15;461(2):124-131
• All: 2 reference(s)