Oosp2^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Oosp2^em1Osb
• Name: oocyte secreted protein 2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6438185
• Synonyms: Oosp2^-11
• Gene: Oosp2 Location: Chr19:11624648-11637923 bp, - strand Genetic Position: Chr19, 8.47 cM
• Alliance: Oosp2^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated an 11 bp deletion resulting in a frameshift mutation of Q62S with a premature stop codon introduced 25 amino acids later. (J:288974)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Oosp2 Mutation: 12 strains or lines available

References

• Original: J:288974 Abbasi F, et al., CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice. Cells. 2020 Mar 28;9(4):821
• All: 1 reference(s)