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Ttll8em1(IMPC)Hmgu
Endonuclease-mediated Allele Detail
Summary
Symbol: Ttll8em1(IMPC)Hmgu
Name: tubulin tyrosine ligase-like family, member 8; endonuclease-mediated mutation 1, Helmholtz Zentrum Muenchen GmbH
MGI ID: MGI:6441116
Gene: Ttll8  Location: Chr15:88774836-88838621 bp, - strand  Genetic Position: Chr15, 44.39 cM
Alliance: Ttll8em1(IMPC)Hmgu page
IMPC: Ttll8 gene page
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Helmholtz-Zentrum Muenchen by injecting CAS9 Protein and 4 guide sequences CCCACTGGAAGATCTGATCCTAT, CCCACCAAACTGCTGTTAGGGTG, CCTTGATATCTCTGCCCAAGGCC, ACTAAACACTGTACTGTCCCAGG, which resulted in a Exon Deletion. (J:265051)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ttll8 Mutation:  38 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory