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Dgkgtm1Yash
Targeted Allele Detail
Summary
Symbol: Dgkgtm1Yash
Name: diacylglycerol kinase, gamma; targeted mutation 1, Yasuhito Shirai
MGI ID: MGI:6441172
Synonyms: Dgkgtm1a
Gene: Dgkg  Location: Chr16:22287211-22475971 bp, - strand  Genetic Position: Chr16, 13.37 cM
Alliance: Dgkgtm1Yash page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:288365
Parent Cell Line:  EGR-G101 (ES Cell)
Strain of Origin:  C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsTargeting vector PRPGS00045_A_B02 was acquired from the International Knockout Mouse Consortium (IKMC). In this vector, intron 3 contains an FRT site, an IRES:lacZ trapping cassette, a loxP site, a promoter-driven neomycin resistance gene cassette, a second FRT site, and a second loxP site. Intron 5 contains a third loxP site. Thus this is a conditional-ready knockout-first reporter allele. (J:288365)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dgkg Mutation:  56 strains or lines available
References
Original:  J:288365 Tsumagari R, et al., DGKgamma Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCgamma. eNeuro. 2020 Mar/Apr;7(2):ENEURO.0319-19.2020
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory