Gpr89^ex
Chemically induced Allele Detail

Summary

• Symbol: Gpr89^ex
• Name: G protein-coupled receptor 89; explorer
• MGI ID: MGI:6441474
• Gene: Gpr89 Location: Chr3:96775630-96812662 bp, - strand Genetic Position: Chr3, 42.01 cM, cytoband F2
• Alliance: Gpr89^ex page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: A G-to-A mutation in the 5th base of intron 10 causes skipping of the 93 bp exon 10 and the loss of the corresponding 31 amino-acids (273-303) from the encoded peptide. A small amount of full-length transcript is still produced. (J:287198)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr89 Mutation: 36 strains or lines available

References

• Original: J:287198 Zhong X, et al., Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8563-8572
• All: 1 reference(s)