Sipa1l2^tm1Mrkr
Targeted Allele Detail

Summary

• Symbol: Sipa1l2^tm1Mrkr
• Name: signal-induced proliferation-associated 1 like 2; targeted mutation 1, Michael R Kreutz
• MGI ID: MGI:6441768
• Gene: Sipa1l2 Location: Chr8:126144802-126296547 bp, - strand Genetic Position: Chr8, 73.63 cM
• Alliance: Sipa1l2^tm1Mrkr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286683
• Parent Cell Line: CCB (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 2 was replaced with an IRES-lacZ-neo reporter selection cassette, creating a knockout allele. (J:286683)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sipa1l2 Mutation: 90 strains or lines available

References

• Original: J:286683 Andres-Alonso M, et al., SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals. Nat Commun. 2019 Nov 29;10(1):5448
• All: 1 reference(s)