Tuba4a^m1Frla
Chemically induced Allele Detail

Summary

• Symbol: Tuba4a^m1Frla
• Name: tubulin, alpha 4A; mutation 1, Francois Lanza
• MGI ID: MGI:6441799
• Synonyms: Tuba4a^Plt68, Tuba4a^V260E
• Gene: Tuba4a Location: Chr1:75190872-75196509 bp, - strand Genetic Position: Chr1, 38.63 cM, cytoband C3
• Alliance: Tuba4a^m1Frla page

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Chemically induced (ENU) (Hypomorph)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis created a T-to-A mutation that results in the substitution of valine codon 260 with glutamic acid (p.V260E). (J:286522)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tuba4a Mutation: 30 strains or lines available

References

• Original: J:286522 Strassel C, et al., An essential role for alpha4A-tubulin in platelet biogenesis. Life Sci Alliance. 2019 Feb;2(1)
• All: 1 reference(s)