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Ccdc198em1(IMPC)Ccpcz
Endonuclease-mediated Allele Detail
Summary
Symbol: Ccdc198em1(IMPC)Ccpcz
Name: coiled-coil domain containing 198; endonuclease-mediated mutation 1, Institute of Molecular Genetics
MGI ID: MGI:6442544
Synonyms: Fame KO
Gene: Ccdc198  Location: Chr14:49463815-49482902 bp, - strand  Genetic Position: Chr14, 25.46 cM, cytoband C1
Alliance: Ccdc198em1(IMPC)Ccpcz page
IMPC: Ccdc198 gene page
Mutation
origin
Strain of Origin:  C57BL/6NCrl
Project Collection: IMPC
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele from IMPC was generated at Czech centre for Phenogenomics by injecting CAS9 Protein and 2 guide sequences CCGACTAGTCTGTACTGGAAATG, CCAAGTGCTAGATTCAGGTCCTT, which resulted in an Exon Deletion. A founder harboring a 661 bp deletion overlapping the entire exon 3 of the gene was used for subsequent breeding. (J:265051, J:337480)
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccdc198 Mutation:  16 strains or lines available
References
Original:  J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory