Dut^em1Bgv
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dut^em1Bgv
• Name: deoxyuridine triphosphatase; endonuclease-mediated mutation 1, Beata G Vertessy
• MGI ID: MGI:6443640
• Synonyms: D47
• Gene: Dut Location: Chr2:125089110-125100528 bp, + strand Genetic Position: Chr2, 61.33 cM
• Alliance: Dut^em1Bgv page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 47 bp deletion leading to a frameshift and early stop codons. (J:290004)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dut Mutation: 14 strains or lines available

References

• Original: J:290004 Palinkas HL, et al., CRISPR/Cas9-Mediated Knock-Out of dUTPase in Mice Leads to Early Embryonic Lethality. Biomolecules. 2019 Apr 4;9(4):136
• All: 1 reference(s)