Cyrib^{tm1d(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Cyrib^{tm1d(KOMP)Wtsi}
• Name: CYFIP related Rac1 interactor B; targeted mutation 1d, Wellcome Trust Sanger Institute
• MGI ID: MGI:6444894
• Gene: Cyrib Location: Chr15:63800946-63932327 bp, - strand Genetic Position: Chr15, 28.16 cM
• Alliance: Cyrib^{tm1d(KOMP)Wtsi} page
• IMPC: Cyrib gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:282597
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Expression:

  In Structures Affected by this Mutation:

  2 anatomical structure(s)

• Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
  • Carrying any Cyrib Mutation: 88 strains or lines available
• References:
  • Original: J:282597 Yuki KE, et al., CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection. Nat Microbiol. 2019 Sep;4(9):1516-1531
  • All: 1 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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