Btbd3^em1Dul
Endonuclease-mediated Allele Detail

Summary

• Symbol: Btbd3^em1Dul
• Name: BTB domain containing 3; endonuclease-mediated mutation 1, Stephanie C Dulawa
• MGI ID: MGI:6446945
• Synonyms: Btbd3^flox
• Gene: Btbd3 Location: Chr2:138098478-138129344 bp, + strand Genetic Position: Chr2, 68.28 cM
• Alliance: Btbd3^em1Dul page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inerted in intron 1 and 2 using CRISPR/Cas9 technology, creating a conditional-ready allele with exon 2 floxed. (J:291459)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btbd3 Mutation: 51 strains or lines available

References

• Original: J:291459 Thompson SL, et al., Btbd3 expression regulates compulsive-like and exploratory behaviors in mice. Transl Psychiatry. 2019 Sep 9;9(1):222
• All: 1 reference(s)