Dp(11Pigs-Nlk)1Kkgg
Targeted Allele Detail

Summary

• Symbol: Dp(11Pigs-Nlk)1Kkgg
• Name: duplication, Chr 11, Kathy K Griendling 1
• MGI ID: MGI:6448073
• Synonyms: Dp1Geno
• Gene: Dp(11Pigs-Nlk)1Kkgg Location: unknown Genetic Position: Chr11, Syntenic

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Duplication, Insertion
• Dp(11Pigs-Nlk)1Kkgg involves 22 genes/genome features (Pigs, Unc119, Foxn1 ...) View all
• Mutation details: While creating a conditional knockout model of Poldip2 with a floxed exon 4 an unexpected mutation duplicated Chromosome 11, from 78,328,894 to 78,634,062 in GRCm38.p6. The 305 kb duplication comprising at least 15 genes. The duplicated segments are located side by side, in the same orientation. Each segment includes a different allele of Poldip2: one wild type and one with a floxed exon 4. (J:316399)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dp(11Pigs-Nlk)1Kkgg Mutation: 0 strains or lines available

References

• Original: J:316399 LassegueI B, et al., Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting. PLoS One. 2021;16(12)
• All: 1 reference(s)