Acadvl^em1(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Acadvl^em1(IMPC)H
• Name: acyl-Coenzyme A dehydrogenase, very long chain; endonuclease-mediated mutation 1, Harwell
• MGI ID: MGI:6449034
• Gene: Acadvl Location: Chr11:69901009-69906237 bp, - strand Genetic Position: Chr11, 42.96 cM, cytoband B2-B5
• Alliance: Acadvl^em1(IMPC)H page
• IMPC: Acadvl gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 4 guide sequences CCGAATCTTCCGTTGTTGAGGAT, GCTACATCGGATCCACTCGAGGG, TCCCGAATCTTCCGTTGTTGAGG, ATCCACTCGAGGGCTCTGTTAGG, which resulted in a Indel. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Acadvl Mutation: 31 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)