Foxp3^{em4(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Foxp3^{em4(cre/ERT2)Smoc}
• Name: forkhead box P3; endonuclease-mediated mutation 4, Shanghai Model Organisms Center
• MGI ID: MGI:6449827
• Synonyms: Foxp3^{em4(IRES-tdTomato-2A-CreERT2)Smoc}, Foxp3-IRES-tdTomato-2A-CreERT2
• Gene: Foxp3 Location: ChrX:7445915-7461482 bp, + strand Genetic Position: ChrX, 3.41 cM
• Alliance: Foxp3^{em4(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase, Reporter)
• Inducer: tamoxifen
• Mutation: Insertion
• Foxp3^{em4(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxp3 (MGI:1891436)

• Mutation details: A IRES-tdTomato-2A-CreERT2 expression cassette was knocked into the stop codon site via CRISPR/Cas mediated recombination. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxp3 (mouse) Summary of all recombinase alleles driven by Foxp3. Alliance mouse Foxp3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxp3 Mutation: 58 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)