Ndc80^tm1Tski
Targeted Allele Detail

Summary

• Symbol: Ndc80^tm1Tski
• Name: NDC80 kinetochore complex component; targeted mutation 1, Tomoya S Kitajima
• MGI ID: MGI:6449895
• Synonyms: Ndc80^f
• Gene: Ndc80 Location: Chr17:71803095-71833852 bp, - strand Genetic Position: Chr17, 41.87 cM, cytoband E2
• Alliance: Ndc80^tm1Tski page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:292307
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 2 was flanked by loxP sites and an frt-flanked neomycin selection cassette was inserted after the first loxP site. (J:292307)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndc80 Mutation: 36 strains or lines available

References

• Original: J:292307 Yoshida S, et al., Prc1-rich kinetochores are required for error-free acentrosomal spindle bipolarization during meiosis I in mouse oocytes. Nat Commun. 2020 May 27;11(1):2652
• All: 1 reference(s)