Grxcr2^tm1Dck
Targeted Allele Detail

Summary

• Symbol: Grxcr2^tm1Dck
• Name: glutaredoxin, cysteine rich 2; targeted mutation 1, David Kohrman
• MGI ID: MGI:6450519
• Synonyms: Grxcr2^flox-neo
• Gene: Grxcr2 Location: Chr18:42118388-42132114 bp, - strand Genetic Position: Chr18, 22.14 cM
• Alliance: Grxcr2^tm1Dck page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265041
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 1. (J:265041)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grxcr2 Mutation: 13 strains or lines available

References

• Original: J:265041 Avenarius MR, et al., Grxcr2 is required for stereocilia morphogenesis in the cochlea. PLoS One. 2018;13(8):e0201713
• All: 1 reference(s)