Pkd2l1^tm1(cre)Lmn
Targeted Allele Detail

Summary

• Symbol: Pkd2l1^tm1(cre)Lmn
• Name: polycystic kidney disease 2-like 1; targeted mutation 1, Emily Liman
• MGI ID: MGI:6451758
• Synonyms: Pkd21l-Cre
• Gene: Pkd2l1 Location: Chr19:44136076-44180881 bp, - strand Genetic Position: Chr19, 36.91 cM
• Alliance: Pkd2l1^tm1(cre)Lmn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229688
• Parent Cell Line: EC7.1 (ES Cell)
• Strain of Origin: (C57BL/6J x 129X1/SvJ)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Pkd2l1^tm1(cre)Lmn expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pkd2l1 (MGI:1352448)

• An IRES-Cre construct was inserted immediately after the stop codon. (J:229688)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pkd2l1 (mouse) Summary of all recombinase alleles driven by Pkd2l1. Alliance mouse Pkd2l1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkd2l1 Mutation: 50 strains or lines available

References

• Original: J:229688 Ye W, et al., The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction. Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E229-38
• All: 2 reference(s)