Zdhhc7^tm1.1Wqz
Targeted Allele Detail

Summary

• Symbol: Zdhhc7^tm1.1Wqz
• Name: zinc finger, DHHC domain containing 7; targeted mutation 1.1, Weiqi Zhang
• MGI ID: MGI:6452490
• Gene: Zdhhc7 Location: Chr8:120807834-120828211 bp, - strand Genetic Position: Chr8, 68.93 cM
• Alliance: Zdhhc7^tm1.1Wqz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293082
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/Sv x C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and a FRT-flanked neomycin resistance cassette was inserted upstream of exon 4 and a second loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exon 4 and the selection cassette. (J:293082)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc7 Mutation: 25 strains or lines available

Notes

CV19 ES cells were used to generate mice in J:293082.

References

• Original: J:293082 Hohoff C, et al., Deficiency of the palmitoyl acyltransferase ZDHHC7 impacts brain and behavior of mice in a sex-specific manner. Brain Struct Funct. 2019 Jul;224(6):2213-2230
• All: 2 reference(s)