Fau^tm1.1Smoc
Targeted Allele Detail

Summary

• Symbol: Fau^tm1.1Smoc
• Name: FAU ubiquitin like and ribosomal protein S30 fusion; targeted mutation 1.1, Shanghai Model Organisms Center
• MGI ID: MGI:6452962
• Gene: Fau Location: Chr19:6107977-6109554 bp, + strand Genetic Position: Chr19, 4.34 cM
• Alliance: Fau^tm1.1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293342
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted into exon 1. An additional loxP site and FRT-flanked neomycin resistance cassette were inserted downstream of exon 4. Cre-mediated recombination removed part of exon 1 through exon 4. Western blot analysis confirmed the absence of protein expression. (J:293342)

Expression

In Mice Carrying this Mutation:	18 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fau Mutation: 7 strains or lines available

References

• Original: J:293342 Gu Y, et al., Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice. Mol Reprod Dev. 2015 Jun;82(6):475-88
• All: 2 reference(s)