Prss51^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prss51^em1Osb
• Name: serine protease 51; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:6454670
• Synonyms: Prss51^del
• Gene: Prss51 Location: Chr14:64323683-64335127 bp, + strand Genetic Position: Chr14, 33.35 cM
• Alliance: Prss51^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed 3973 bp encompassing the coding sequence. (J:293896)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Prss51 Mutation: 21 strains or lines available

References

• Original: J:293896 Kobayashi K, et al., Prss55 but not Prss51 is required for male fertility in mice. Biol Reprod. 2020 Aug 4;103(2):223-234
• All: 1 reference(s)