Ctrb1^em1Toth
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctrb1^em1Toth
• Name: chymotrypsinogen B1; endonuclease-mediated mutation 1, Miklos Toth
• MGI ID: MGI:6455002
• Synonyms: Ctrb1-del
• Gene: Ctrb1 Location: Chr8:112413151-112417642 bp, - strand Genetic Position: Chr8, 57.98 cM
• Alliance: Ctrb1^em1Toth page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 4 deleted 79 bp and produced a null allele. (J:294171)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctrb1 Mutation: 17 strains or lines available

References

• Original: J:294171 Jancso Z, et al., Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice. Gastroenterology. 2018;155(4):1017-1021
• All: 2 reference(s)