Zc4h2^em1.1Yqd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zc4h2^em1.1Yqd
• Name: zinc finger, C4H2 domain containing; endonuclease-mediated mutation 1.1, Yu-qiang Ding
• MGI ID: MGI:6455141
• Synonyms: ZC4H2^-, Zc4h2 KO
• Gene: Zc4h2 Location: ChrX:94682799-94702115 bp, - strand Genetic Position: ChrX, 41.99 cM
• Alliance: Zc4h2^em1.1Yqd page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 2 was deleted via Cre-mediated recombination of flanking loxP sites. (J:291948)

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zc4h2 Mutation: 1 strain or line available

References

• Original: J:291948 Ma P, et al., ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling. J Mol Cell Biol. 2020 Jun 11;12(5):337-344
• All: 2 reference(s)