Fhod1^tm1.1Ryut
Targeted Allele Detail

Summary

• Symbol: Fhod1^tm1.1Ryut
• Name: formin homology 2 domain containing 1; targeted mutation 1.1, Ryu Takeya
• MGI ID: MGI:6455142
• Gene: Fhod1 Location: Chr8:106055795-106074585 bp, - strand Genetic Position: Chr8, 53.04 cM
• Alliance: Fhod1^tm1.1Ryut page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:293832
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The tareting vector replaced exon 1 with a lox71 site, lacZ reporter gene, FRT site, neomycin resistance cassette, FRT site, and loxP site. Flp-mediated recombination removed the selection cassette. (J:293832)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fhod1 Mutation: 57 strains or lines available

References

• Original: J:293832 Sanematsu F, et al., Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice. Cytoskeleton (Hoboken). 2019 Feb;76(2):219-229
• All: 1 reference(s)