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Kansl3tm1.1Max
Targeted Allele Detail
Summary
Symbol: Kansl3tm1.1Max
Name: KAT8 regulatory NSL complex subunit 3; targeted mutation 1.1, Max Planck Institut fur Immunbiologie
MGI ID: MGI:6455408
Synonyms: Kansl3fl
Gene: Kansl3  Location: Chr1:36374811-36408262 bp, - strand  Genetic Position: Chr1, 15.22 cM
Alliance: Kansl3tm1.1Max page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:291094
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 3 and 4 were floxed. The selection cassette was removed. (J:291094)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 32 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kansl3 Mutation:  41 strains or lines available
References
Original:  J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory